Krabbe disease (KD) is a childhood leukodystrophy with no cure currently available.KD is due to a deficiency of a lysosomal enzyme called galactosyl-ceramidase (GALC) and is characterized by the accumulation in the nervous system of the sphingolipid psychosine (PSY), whose cytotoxic molecular mechanism is not fully known yet.Here, we study the expr
Studies of cooking-generated NO2 effects are rare in occupational epidemiology.In the present study, we evaluated the lung function of professional cooks exposed to NO2 in hospital kitchens.We performed spirometry in 37 cooks working in four hospital kitchens and estimated the predicted FVC, FEV1 and FEF25-75, based on age, sex, race, weight, and h
Trigeminal sensory neuropathy MAGNESIUM STRAWBERRY can be caused by a variety of conditions, including local, traumatic, iatrogenic, or systemic causes.Diagnosis and management remain a challenge for maxillofacial surgeons and neurologists.Therefore, a good clinical examination and objective tests and imaging are needed when diagnosing patients who
Efficient water supply is very crucial to sustenance of socio-economic growth, poverty attenuation, and food security.In most rural areas of developing countries including Nigeria water supplies are not commensurate with demand leading to a shortfall in water use and many people suffer from this scenario.This research investigated the factors respo